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PAI I ERNS AND GAPS <br />What We Know: <br />• Use among youth (12-17) has not increased in recent years <br />despite decreased perception of risk <br />• Current users use more often (daily, nearly daily) than in 2002 <br />• Potency is increasing; plant components are changing <br />• Cannabis is being administered through different routes <br />C1(PIw7- <br />What We Need to Know: <br />• Need improved measures of frequency, dosage, patterns of use <br />• Persuasive Messaging (especially for youth) to counter the trend of decreasing <br />harm perception <br />• Greater knowledge of the impact of changing potency (user titration?), <br />constituents, and alternative routes of administration D <br />• Regional differences based on changing laws, policies, and social norms <br />• Use of other substances: complementarity vs. substitution <br />