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6.1.D. - Page 25 <br />by non -opioid drugs (such as cocaine, LSD, ecstasy (Molly), sedatives, tranquilizers or <br />marijuana) or alcohol; antagonizes opioid effects such as respiratory depression, analgesia, and <br />miosis. Repeat doses often needed due to naloxone's action time being shorter than the effects of <br />many opioids. <br />Intranasal Naloxone - a mucosal atomization device, drug is a fine mist sprayed into nasal <br />cavity; works quickly and painlessly in vascular mucosa to absorb naloxone directly into <br />the bloodstream (slightly slower than intramuscular or intra -venous injections), minimal <br />training involved for law enforcement personnel and trained friends or relatives of <br />overdose victims to use; may need repeated doses. Commonly known brand name for <br />intranasal naloxone is Narcan®. <br />Narcan® - the commercial brand name of the intranasal prescription medicine, naloxone <br />(HCL), used for the treatment of an opioid emergency such as a possible overdose with <br />signs of breathing problems, severe sleepiness or nonresponsiveness. NARCAN Nasal <br />Spray is the FDA -approved nasal form of naloxone for the emergency treatment of a <br />known or suspected life-threatening opioid overdose. The side-effects of Narcan are <br />minimal, though its use may result in symptoms of acute opioid withdrawal in overdose <br />patient. <br />Opioid Overdose - an opioid overdose (OD) is the body's response to being overwhelmed or <br />poisoned by too much of a substance. Overdoses can be but are not always life-threatening or life <br />ending. They can result in unconsciousness, respiratory depression or failure, sleepiness, <br />contracted pupils, unresponsive, seizures, possible bluish skin color indicating lack of oxygen, <br />cold, clammy skin, irregular or stopped, faint pulse. failed breathing, heart failure, and seizures. <br />Many overdoses are the result of taking drugs of inconsistent or unknown strength or drugs that <br />are mixed with other substances. <br />Scheduled Drugs - in 1971, under Title II of the Comprehensive Drug Abuse Prevention and <br />Control Act, a federal drug policy was established for the United States regulating the <br />manufacture, import, use, possession and distribution of categories of specific substances. Five <br />Schedules (or classifications) were created, identifying drugs and other substances that met the <br />qualifications and restrictions for each category. The Drug Enforcement Administration (DEA) <br />classifies opioids and other drugs into three schedules (II, III, and IV), based upon their abuse <br />potential and relative risks. For example, Schedule II includes drugs such as heroin or other <br />substances with high potential for abuse, having no medical use, and determined medically <br />unsafe. <br />2017-2018 San Mateo County Civil Grand Jury G2 <br />