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1732 INTERNATIONAL JOURNAL OF EPIDEMIOLOGY <br />Table 2 Random effects meta-analysis and univariate meta -regression of studies on gas cooking and asthma stratified by <br />age, study region, proportion of gas cooking and year of publication <br />Number Summary odds 12 (heterogeneity Ratio of odds <br />of studies ratio (95% Cl) P -value) ratios (95% Cl)' <br />Current asthma <br />Age of participants <br /><6years <br />3 <br />1.22 <br />(0.95-1,56) <br />0.0% (0.504) <br />1.00 <br />(mf) <br />6-I0 years <br />4 <br />1,51 <br />(1,12-2.02) <br />33.5% (0.211) <br />1.25 <br />(0.82-1.90) <br />>10 years <br />4 <br />1.54 <br />(1.16-2.06) <br />0.0% (0.500) <br />1.27 <br />(0.80-2.03) <br />Study region <br />Europe <br />7 <br />1.34 <br />)1.13-1.60) <br />0.0% (0.666) <br />1.00 <br />(req <br />North America <br />3 <br />1.36 <br />(0.76-2.43) <br />68.7% (0.041) <br />1.13 <br />(0,74-1.71) <br />0 <br />Asia-Pacific <br />1 <br />1.50 <br />(1.01-2.23) <br />OA% (0.937) <br />1.11 <br />(0.65-L89) o <br />Proportion of gas cooking° <br />n <br /><30% <br />4 <br />L79 <br />(1.38-2.33) <br />0.0% (0.615) <br />1.00 <br />(tel') 3 <br />i30% <br />6 <br />132 <br />(1.12-1.56) <br />0.0% (0.655) <br />0.74 <br />(0.52-1.05) <br />Publication year <br />Before 2000 <br />2 <br />1.76 <br />(1,37-2.25) <br />0.0% (0.597) <br />1.00 <br />(ref) 0 <br />2000 or later <br />9 <br />1.30 <br />( 1.10-1.53) <br />0.0% (0.601) <br />0.74 <br />(0.53-1.03) m <br />3 <br />Lifetime asthma <br />Age of participants <br />0 <br />_<6years <br />2 <br />1.38 <br />(0.98-1.94) <br />0.0% (0.506) <br />1.00 <br />(ref) o <br />6-10 years <br />3 <br />1.16 <br />(0.95-1.41) <br />0.0% (0.375) <br />0.83 <br />(0.41-1.67) 3 <br />>10 years <br />3 <br />1.28 <br />(0.50-329) <br />65.3% (0.056) <br />0.92 <br />m <br />(0.33-2.53) <br />Study region <br />° <br />m <br />Europe <br />t <br />1.33 <br />(0.92-1.93) <br />- <br />LOO <br />(req o, <br />North America <br />3 <br />0.86 <br />(U60-1.24) <br />0.0% (0412) <br />0.65 <br />(0.31-1.37) <br />Asia-Pacific <br />4 <br />1.32 <br />(1.to- 1,59) <br />28.7%(0.240) <br />0.96 <br />(0.55-1.68) c <br />Proportion of gas cooking" <br />c <br /><30% <br />3 <br />1,27 <br />((Y87 -I.84) <br />53.8% (0.115) <br />1.00 <br />(req <br />>,30% <br />3 <br />1,07 <br />(0.65-1.76) <br />10.4% (0.188) <br />0.98 <br />(0.62-1.53) <br />V <br />Year of publication <br />V <br />Before 2000 <br />4 <br />1.24 <br />(0.93-1.65) <br />37.2% (0.189) <br />1.00 <br />(rel) m <br />2000 of later <br />3 <br />1.25 <br />(0.93-1.68) <br />44.0% (0,148) <br />L02 <br />(0.68-1.54) <br />All asthma` <br />as <br />m <br />Age of participants <br />0 <br />_<6 years <br />5 <br />1.26 <br />(1.12-1.42) <br />0.0% (0.506) <br />1.00 <br />(req <br />10 years <br />7 <br />1.31 <br />(L08-1.59) <br />31)_8% (0.133) <br />1.03 <br />tQ <br />((1.79-1.35)W <br />>10 years <br />7 <br />1.45 <br />(1.07-1.97) <br />26.6% (0.217) <br />1.27 <br />(1.05-1.54) 9 <br />Study region <br />m <br />9 <br />Europe <br />8 <br />1.34 <br />(1.15-1.57) <br />0.0% (0.763) <br />1.00 <br />C' <br />(ref) R <br />North America <br />6 <br />1.12 <br />(0.73-1.73) <br />66.7% (0.010) <br />0.92 <br />N <br />10.69-1.23) a <br />Asian -Pacific <br />5 <br />1.29 <br />(1,15-1,45) <br />0.0% (0.442) <br />1,01 <br />(0.76-1.35) <br />Proportion of gas cooking" <br /><30% <br />7 <br />1.45 <br />(1.12-1,87) <br />40.1% (0.124) <br />1.00 <br />(ml) <br />>-30% <br />10 <br />1.25 <br />(1.13-1.38) <br />0.0%(0.617) <br />0.86 <br />(0.68-1.06) <br />Publication year <br />Before 2000 <br />6 <br />1.42 <br />(1.13-1.80) <br />50.0% (0.062) <br />1.00 <br />(ref) <br />2000 or Tater <br />13 <br />1.28 <br />(1.13-1.45) <br />0.0% (0.467) <br />0,93 <br />(0.75-1.16) <br />aRatios of odds ratios are the odds ratio from studies with the characteristic divided by the odds ratios from studies of the reference <br />category and were calculated from coefficients of meta -regression b as exp(b). Ratios above 1.0 indicate a larger odds ratio for <br />studies with the characteristic. <br />binformation of proportion of gas cooking was not available in two studies (Garrett or al. 1998; Tavernier el a1, 2005). Belanger of al. <br />(2006) was counted twice in this analysis as results were presented fmmulti-family and single-family homes separately, and <br />proportions for gas cooking were X30% for multifamily homes and <30% for single-family homes, respectively. <br />cCurrent + lifetime. <br />